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<br /> BioProcess<br /> International<br /> DIGITAL EDITION<br /> ARCHIVE<br /> BioProcess<br /> International<br /> CONJUGATES<br /> September 2023<br /> DIVERSE The Rise of Antibody–Drug Conjugates and<br /> Related Modalities: Innovations and Partnerships<br /> Lead the Way . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . C2<br /> PLATFORMS Gareth Macdonald<br /> Developers Work To Refine Platforms for<br /> the Best Results . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4<br /> EXPAND THE Cheryl Scott<br /> Manufacturing Challenges of Therapeutic<br /> TOOLKIT Antibody–Drug Conjugates . . . . . . . . . . . . . . <a title="September 2023 - Featured Report page 1" href="https://secure.viewer.zmags.com/publication/f8e1dab8?page=1"> BioProcess International DIGITAL EDITION ARCHIVE</a> <a title="September 2023 - Featured Report page 2" href="https://secure.viewer.zmags.com/publication/f8e1dab8?page=2"> BioProcess International CONJUGATES Septemb</a> <a title="September 2023 - Featured Report page 3" href="https://secure.viewer.zmags.com/publication/f8e1dab8?page=3"> The Rise of Antibody–Drug Conjugates and Related </a> <a title="September 2023 - Featured Report page 4" href="https://secure.viewer.zmags.com/publication/f8e1dab8?page=4"> mid-1970s that scientists could target medicines </a> <a title="September 2023 - Featured Report page 5" href="https://secure.viewer.zmags.com/publication/f8e1dab8?page=5"> A surge in research collaborations between compan</a> <a title="September 2023 - Featured Report page 6" href="https://secure.viewer.zmags.com/publication/f8e1dab8?page=6"> vaccine), which protects against the bacteria res</a> <a title="September 2023 - Featured Report page 7" href="https://secure.viewer.zmags.com/publication/f8e1dab8?page=7"> Developers Work To Refine Platforms for the Best </a> <a title="September 2023 - Featured Report page 8" href="https://secure.viewer.zmags.com/publication/f8e1dab8?page=8"> this featured report. To overcome those limitatio</a> <a title="September 2023 - Featured Report page 9" href="https://secure.viewer.zmags.com/publication/f8e1dab8?page=9"> developed during the conjugation reaction. As pre</a> <a title="September 2023 - Featured Report page 10" href="https://secure.viewer.zmags.com/publication/f8e1dab8?page=10"> bivalent conjugation to a bromoacetylated peptide</a> <a title="September 2023 - Featured Report page 11" href="https://secure.viewer.zmags.com/publication/f8e1dab8?page=11"> Manufacturing Challenges of Therapeutic Antibody–</a> <a title="September 2023 - Featured Report page 12" href="https://secure.viewer.zmags.com/publication/f8e1dab8?page=12"> Figure 1B: Antibody–drug conjugate (ADC) structur</a> <a title="September 2023 - Featured Report page 13" href="https://secure.viewer.zmags.com/publication/f8e1dab8?page=13"> Full-length antibodies can be purified using PLAT</a> <a title="September 2023 - Featured Report page 14" href="https://secure.viewer.zmags.com/publication/f8e1dab8?page=14"> Table 1: Antibody–drug conjugate (ADC) linker che</a> <a title="September 2023 - Featured Report page 15" href="https://secure.viewer.zmags.com/publication/f8e1dab8?page=15"> Figure 3: Idealized size-exclusion chromatography</a> <a title="September 2023 - Featured Report page 16" href="https://secure.viewer.zmags.com/publication/f8e1dab8?page=16"> Figure 4B: Example linker–toxin (LT) coupling and</a> <a title="September 2023 - Featured Report page 17" href="https://secure.viewer.zmags.com/publication/f8e1dab8?page=17"> Figure 6: In this generalized process flow for AD</a> <a title="September 2023 - Featured Report page 18" href="https://secure.viewer.zmags.com/publication/f8e1dab8?page=18"> Table 2: Analytical methods for ADC development a</a> <a title="September 2023 - Featured Report page 19" href="https://secure.viewer.zmags.com/publication/f8e1dab8?page=19"> new applications for conjugated antibody products</a> <a title="September 2023 - Featured Report page 20" href="https://secure.viewer.zmags.com/publication/f8e1dab8?page=20"> 29 Nguyen TD, Bordeau BM, Balthasar JP. Mech</a> <a title="September 2023 - Featured Report page 21" href="https://secure.viewer.zmags.com/publication/f8e1dab8?page=21"> STRONGER AS ONE WuXi XDC - Your One-Stop Antibo</a>