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ALLERGY &
IMMUNOLOGY
ISSN 2398-9130 Vol 3.1 • July 2018 • europeanmedical-journal.com
INSIDE
Review of
EAACI 2018
Munich, Germany
Contents
EDITORIAL BOARD 4
01 CONGRESS REVIEW
Review of EAACI 2018, held in Munich, Germany, 26th–30th May 2018 10
02 INTERVIEWS WITH EMJ ALLERGY & IMMUNOLOGY
EDITORIAL BOARD
Dr Michael Rudenko 23
Dr James Woijoo Kim 25
Dr Philippe Bégin 28
ALLERGY & IMMUNOLOGY ISSN 2398-9130
Contents EDITORIAL BOARD
"...I take great pleasure in welcoming you
Editorial Board Editor-in-Chief Prof Dr Jacques B
Aims and Scope The European Medical Journal (EMJ)
EMJ Allergy Immunol. Chief Executive Officer Spen
Welcome Munich, Germany, this year played host to
Our latest videos: EAACI
Foreword Dear friends, colleagues, and readers al
Congress Review Review of the European
responses. With global events such as the Olympic
Other announcements made at the Opening Ceremony
‘Diesel Gate’: Should More be Done to Combat Air
Innovative Pollen Detector Keeps Bavarians One St
16 ALLERGY & IMMUNOLOGY • July 2018
Internationales Congress Center München
The EAACI Clinical Village REFERRED to as one of
Congress Technology at its Finest TECHNOLOGICAL
Congress Feature Prof Jacques Bouchard
EMJ Allergy & Immunology Editorial Board Me
DPA-Dx* – a milestone in allergy diagnostics Pre
Interviews Take the opportunity to learn more a
market and many more in the pipeline. I think tha
Finally, what advice do you have for
"I believe these organisations have a very imp
presentation after theirs. I did not sleep much t
Dr Philippe Bégin Université de Montréal, Canada
How do you think OIT will affect the lives of pat
differences. The first difference is that there ar
Prof Nikos Papadopoulos University of Manchester,
we are opening a field for these possibilities to
Available now. ME
Take a Breath of Real-World Evidence This com
The benefits of RW research can be illustrated by
The benefits of exploring RW data in the context o
large RW sample sizes quickly and efficiently. Li
>45 years; for the controls, 6% were aged 5–17 ye
follow-up was -28.6% greater for AIT patients tha
Allergoids: Ready for the Future This sympo
Meeting Summary Improving therapy for people with
AI0903rB13 20, 80, 160, 320 µg rBet v1-FV Phase I
SCIT with rPhleum The first proof-of-concept st
These general problems have also occurred wi
included early-phase response 20 minutes after in
Overall, investigational HDM allergoid SC
using only the 10,000 TU/mL vial will allo
Large studies, including the ongoing Phase III AL
24. Bauchau V, Durham SR. Prevalence 31.
Towards Optimised Management of Cow’s Milk Pro
immaturity, which has been associated with an inc
IgE-mediated CMPA Atopic dermatitis Diarrh
There were differences in per
How to Define Extensively Hydrolysed Formula for
7 of the 8 whey-based eHF. Overall, the analyses
Significant variation in the peptide molecular wei
allergens in germ-free mice, reducing the IgE res
Three fundamental themes explored during this
29. Thompson-Chagoyan OC et al. Faecal m
Raising the Clinical Bar Beyond Current Biologics
Meeting Summary Asthma is a heterogeneous disease
Type 2 Inflammation is Associated with Multiple
other non-biologic controller therapy add-ons (tr
controlled asthma. Agents undergoing Phase III cl
Placebo SC 200 mg Q2W Placebo SC 300 mg Q2W 0.6
≥50 ppb and ≥25 ppb FeNO levels were assoc
Despite these reductions in corticosteroid dosing
Asthma. 2010;47(2):124-30. 20
49. Ortega HG et al. Mepolizumab treatme
Abstract Reviews From food allergies to vaccine
In this study, we investigated the epigenet
Evaluation of a Treatment Scheme wit
placebo was achieved with all active dosing
Microcrystalline Tyrosine: An Appropriate Alterna
Both Alum and MCT were found to activate the infla
microbial origin. Allergens thereby can act
asthma (SA) and chronic idiopathic urticaria
However, as omalizumab treatment continues, not
agglomerated in a single cluster,
in surveillance, prevention, and treatmen
Interact with us on social med
Asthma and Food Allergies The rela
BACKGROUND There is a long-established li
ASTHMA Asthma is a chronic disease
peanut protein in the home environment by m
associated with poorer outcomes for children with
References 1. Tamari M et al. Genome-wide
on the management of asthma: Quick reference guid
The Oligosaccharide Galactose-α-1,3-Galactose and
INTRODUCTION It has been 10 years since the
meat experienced a hypersensitivity reaction
A B α-Gal epitope NH R Gal
unaware of any other common food allergen that is
Specific information about dieta
The mechanism of sensitisation is unclear, b
the reactions were reported within 2 hours.
Antibody as Foe Turned Friend 27. i
57. Apostolovic D et al. Immunoprofile of
Allergy to Stinging Insects: Diagnosis and Manage
Table 1: Hymenoptera characteristics and avoidanc
and Clinical Immunology (EAACI) Task Force o
Quirt et al.21 advocate using a single ste
Venom Immunotherapy It is important to know that
Identifying Risk Factors for Anaphylaxis Certain
Med J Aust. 2011;195(2):69-73. 15
Autoinflammatory Diseases: Consequences of Uncont
available on AD. In 2013, a study1 estimated the
extracellular pathogen recognition by a toll
The most widely studied and best characterised of
result in another NLRP3-associated AD, termed Maj
their ability to modulate the pathogenesis and pr
References 1. Hemminki K et al. Incidence
Mediterranean fever in Armenian 50. po
Genetically Modified Wheat, Wheat Intolerance,
population of Africa accounts for 5.6% of CD ca
Table 1: Immunotoxic gluten peptides and their di
and tolerance to over-mixing, thereby showing bet
mass spectrometry were used to measure the extent
Hurkman et al.,64 while conducting studies to obs
metabolomics in order to make the food safety con
A follow-up and family study. 35
proteomic analysis of the effect of temperature a
Challenges in Allergy Diagnostics and Solutions W
without allergy-focussed clinical history lea
Different Techniques Used to Detect Specific Immun
Substantiation of use of specific activity of mole
References 1. Gupta RS et al. Predicting out
Revising the Criteria for Occupational Mould-Rel
INTRODUCTION Mould-related disease, or dampness a
exposure to A. fumigatus, he underwent his first b
in the extremities, loss of voice, headache
A Oxygen saturation (%) 100 98 96 94 92 90 88 8
health effects of SIC. These cases show that DMHS
have been demonstrated to inhibit the growth and
References 1. Curtis L et al. Adverse health
Events 29TH AUGUST–2ND SEPTEMBER 2018 4TH–8TH SEP
30TH SEPTEMBER–2ND OCTOBER 2018 18TH–20TH OCTOBER
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