<br />
REPRODUCTIVE<br />
HEALTH<br />
ISSN 2059-450X Vol 4.1 • August 2018 • europeanmedical-journal.com<br />
INSIDE<br />
Review of<br />
ESHRE 2018<br />
Barcelona, Spain<br />
Contents<br />
EDITORIAL BOARD 4<br />
WELCOME 7<br />
FOREWORD 9<br />
01 CONGRESS REVIEW<br />
Review of ESHRE 2018, held in Barcelona, Spain, 1st–4th July 2018 12<br />
02 INTERVIEWS WITH EMJ REPRODUCTIVE HEALTH<br />
EDITORIAL BOARD<br />
Dr Ioannis Sfontouris 30<br />
Dr Monica Muratori <a title="EMJ Reproductive Health 4.1 page 1" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=1"> REPRODUCTIVE HEALTH ISSN 2059-450X </a>
<a title="EMJ Reproductive Health 4.1 page 2" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=2"> Contents EDITORIAL BOARD </a>
<a title="EMJ Reproductive Health 4.1 page 3" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=3"> "Publishing this journal has been a real labour </a>
<a title="EMJ Reproductive Health 4.1 page 4" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=4"> Editorial Board Editor-in-Chief Prof Elisabetta B</a>
<a title="EMJ Reproductive Health 4.1 page 5" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=5"> Aims and Scope The European Medical Journal (EMJ)</a>
<a title="EMJ Reproductive Health 4.1 page 6" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=6"> EMJ Repro Health. Chief Executive Officer Spencer</a>
<a title="EMJ Reproductive Health 4.1 page 7" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=7"> Welcome Welcome to this year’s edition of EMJ Rep</a>
<a title="EMJ Reproductive Health 4.1 page 8" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=8"> Leaders in Cryogenic RFID Technology RFID Cryog</a>
<a title="EMJ Reproductive Health 4.1 page 9" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=9"> Foreword Dear colleagues, It is my pleasure to we</a>
<a title="EMJ Reproductive Health 4.1 page 10" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=10"> Available now.</a>
<a title="EMJ Reproductive Health 4.1 page 11" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=11"> Featured inside: Congress Review + Review of M</a>
<a title="EMJ Reproductive Health 4.1 page 12" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=12"> </a>
<a title="EMJ Reproductive Health 4.1 page 13" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=13"> Congress Review 34th Annual Meeting</a>
<a title="EMJ Reproductive Health 4.1 page 14" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=14"> the help of ART was placed under the microscope. </a>
<a title="EMJ Reproductive Health 4.1 page 15" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=15"> Progress Towards Artificial Ovaries ARTIFICAL ovar</a>
<a title="EMJ Reproductive Health 4.1 page 16" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=16"> Therefore, while ICSI is not a cause of or risk f</a>
<a title="EMJ Reproductive Health 4.1 page 17" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=17"> Real-Life Data on Social Egg Freezers Returning f</a>
<a title="EMJ Reproductive Health 4.1 page 18" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=18"> Barcelona International Convention Centre Venue o</a>
<a title="EMJ Reproductive Health 4.1 page 19" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=19"> Creative Commons Attribution-Non Commercial 4.0 </a>
<a title="EMJ Reproductive Health 4.1 page 20" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=20"> New Data for Immunological Treatment for Pregnanc</a>
<a title="EMJ Reproductive Health 4.1 page 21" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=21"> The ICMART report collected data from regional ce</a>
<a title="EMJ Reproductive Health 4.1 page 22" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=22"> Nuts in the Diet Affect Quality of Sperm DIET has</a>
<a title="EMJ Reproductive Health 4.1 page 23" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=23"> Relationship Instability Behind with a part</a>
<a title="EMJ Reproductive Health 4.1 page 24" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=24"> Energising Eggs Does Not Increase Pregnancy Rate </a>
<a title="EMJ Reproductive Health 4.1 page 25" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=25"> "…even based on just our results, I think clinics</a>
<a title="EMJ Reproductive Health 4.1 page 26" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=26"> The study participants numbered 174 couples, and </a>
<a title="EMJ Reproductive Health 4.1 page 27" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=27"> The Danish study used the cancer and </a>
<a title="EMJ Reproductive Health 4.1 page 28" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=28"> Trial Data Supports Anti-Müllerian Hormone Analys</a>
<a title="EMJ Reproductive Health 4.1 page 29" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=29"> Complement your NGS findings with the CytoScan XO</a>
<a title="EMJ Reproductive Health 4.1 page 30" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=30"> Interviews Hear insights from across Europe in</a>
<a title="EMJ Reproductive Health 4.1 page 31" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=31"> To date, the Embryology SIG has focussed on the d</a>
<a title="EMJ Reproductive Health 4.1 page 32" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=32"> How important do you feel ESHRE guidelines and ap</a>
<a title="EMJ Reproductive Health 4.1 page 33" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=33"> Dr Monica Muratori University of Florence, Italy</a>
<a title="EMJ Reproductive Health 4.1 page 34" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=34"> sperm nuclei. Sperm DNA fragmentation is qui</a>
<a title="EMJ Reproductive Health 4.1 page 35" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=35"> and attack by ROS. Apoptosis in testis can be tri</a>
<a title="EMJ Reproductive Health 4.1 page 36" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=36"> the type of cancer and the type and duration of t</a>
<a title="EMJ Reproductive Health 4.1 page 37" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=37"> A research group from the University of Edinburgh</a>
<a title="EMJ Reproductive Health 4.1 page 38" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=38"> chronic heart disease, lipid metabolism disorders</a>
<a title="EMJ Reproductive Health 4.1 page 39" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=39"> should also be avoided (no more than one c</a>
<a title="EMJ Reproductive Health 4.1 page 40" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=40"> challenge, it is a state of mind. We have to keep</a>
<a title="EMJ Reproductive Health 4.1 page 41" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=41"> omnes pro uno: A novel, evidence-based, unifying </a>
<a title="EMJ Reproductive Health 4.1 page 42" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=42"> The Evolution of Assisted Reproductive Techno</a>
<a title="EMJ Reproductive Health 4.1 page 43" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=43"> therefore, personalise treatment accordingly. Of </a>
<a title="EMJ Reproductive Health 4.1 page 44" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=44"> 1910s 1920s 1910 First gonadotrophin </a>
<a title="EMJ Reproductive Health 4.1 page 45" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=45"> capability for prediction of both poor and high r</a>
<a title="EMJ Reproductive Health 4.1 page 46" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=46"> Figure 2: Dose–response model that shows the pred</a>
<a title="EMJ Reproductive Health 4.1 page 47" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=47"> Follitropin Delta: Ovarian Stimulation with Effic</a>
<a title="EMJ Reproductive Health 4.1 page 48" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=48"> (a predefined non-inferiority margin of -8.0%), wh</a>
<a title="EMJ Reproductive Health 4.1 page 49" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=49"> As a result of the ESTHER-1 trial, follitr</a>
<a title="EMJ Reproductive Health 4.1 page 50" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=50"> 17. Devroey P et al.; Menopur in GnRH A</a>
<a title="EMJ Reproductive Health 4.1 page 51" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=51"> Dydrogesterone: Shining New Light on Life This s</a>
<a title="EMJ Reproductive Health 4.1 page 52" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=52"> evaluated in endometrial biopsies. There remains </a>
<a title="EMJ Reproductive Health 4.1 page 53" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=53"> RPL (n=404 active treatment, n=432 placebo), ther</a>
<a title="EMJ Reproductive Health 4.1 page 54" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=54"> Paraffin-block analysis may also be required</a>
<a title="EMJ Reproductive Health 4.1 page 55" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=55"> Leading up to 2012, three prospective, </a>
<a title="EMJ Reproductive Health 4.1 page 56" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=56"> Immune adaptations are finely tuned to an ‘i</a>
<a title="EMJ Reproductive Health 4.1 page 57" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=57"> 16. Carp H. A systematic review of dydr</a>
<a title="EMJ Reproductive Health 4.1 page 58" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=58"> Abstract Reviews Learn more about the reproduct</a>
<a title="EMJ Reproductive Health 4.1 page 59" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=59"> habit, leukocytospermia, semen viscosity, and</a>
<a title="EMJ Reproductive Health 4.1 page 60" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=60"> in 1981.1 Theoretically, flushing would allow for </a>
<a title="EMJ Reproductive Health 4.1 page 61" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=61"> On the contrary, the flushing group</a>
<a title="EMJ Reproductive Health 4.1 page 62" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=62"> Results indicated both a prevalence and</a>
<a title="EMJ Reproductive Health 4.1 page 63" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=63"> A Comprehensive Two-Centre RNA-Seq Study R</a>
<a title="EMJ Reproductive Health 4.1 page 64" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=64"> others. In addition to already known microRNA, a </a>
<a title="EMJ Reproductive Health 4.1 page 65" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=65"> fertility for granted.3 Little is known about the</a>
<a title="EMJ Reproductive Health 4.1 page 66" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=66"> 4. Department of Public Health, University of </a>
<a title="EMJ Reproductive Health 4.1 page 67" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=67"> 7. Lincoln YS, Guba EG, “Paradigmatic controve</a>
<a title="EMJ Reproductive Health 4.1 page 68" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=68"> previous pregnancies) compared to women with prev</a>
<a title="EMJ Reproductive Health 4.1 page 69" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=69"> do not allow fresh embryo transfer. Therefore, th</a>
<a title="EMJ Reproductive Health 4.1 page 70" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=70"> Uterine Microbiota: A Role Beyond Infection </a>
<a title="EMJ Reproductive Health 4.1 page 71" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=71"> words, sequencing results do not enable us </a>
<a title="EMJ Reproductive Health 4.1 page 72" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=72"> Pseudomonas 9.09% </a>
<a title="EMJ Reproductive Health 4.1 page 73" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=73"> A Haematogenous spread of bacteria Uteri</a>
<a title="EMJ Reproductive Health 4.1 page 74" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=74"> In women with endometriosis, the uterin</a>
<a title="EMJ Reproductive Health 4.1 page 75" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=75"> Commun. 2017;8(1):875. 4. Ma B et al. Vaginal </a>
<a title="EMJ Reproductive Health 4.1 page 76" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=76"> Children After Cancer? Meeting Male Patients’ </a>
<a title="EMJ Reproductive Health 4.1 page 77" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=77"> PSYCHOSOCIAL DISTRESS IN MALE CANCER PATIENTS IN</a>
<a title="EMJ Reproductive Health 4.1 page 78" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=78"> population, which includes patients between the a</a>
<a title="EMJ Reproductive Health 4.1 page 79" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=79"> These perceptions are not unique to AYA can</a>
<a title="EMJ Reproductive Health 4.1 page 80" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=80"> description of fertility preservation discussions</a>
<a title="EMJ Reproductive Health 4.1 page 81" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=81"> patients. Both patients and clinicians shoul</a>
<a title="EMJ Reproductive Health 4.1 page 82" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=82"> 36. Kelvin JF, Reinecke J. Institutional </a>
<a title="EMJ Reproductive Health 4.1 page 83" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=83"> A Powerful and Universal Preimplantation Gene</a>
<a title="EMJ Reproductive Health 4.1 page 84" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=84"> INTRODUCTION Preimplantation genetic diagnosis </a>
<a title="EMJ Reproductive Health 4.1 page 85" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=85"> F508 D7S23 AFM320 IVS8 IVS10 IVS1</a>
<a title="EMJ Reproductive Health 4.1 page 86" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=86"> each of the pairs of primers for IVS8CA and CFTRS</a>
<a title="EMJ Reproductive Health 4.1 page 87" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=87"> Twenty-eight couples (90%) had one or two unaffec</a>
<a title="EMJ Reproductive Health 4.1 page 88" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=88"> Reproductive Medicine Involving Mitochondrial DN</a>
<a title="EMJ Reproductive Health 4.1 page 89" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=89"> Mitochondrial functions are exerted through the c</a>
<a title="EMJ Reproductive Health 4.1 page 90" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=90"> Table 1: Clinical implementations of germline mit</a>
<a title="EMJ Reproductive Health 4.1 page 91" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=91"> Table 1 continued. Remarks First live births aft</a>
<a title="EMJ Reproductive Health 4.1 page 92" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=92"> A Maternal spindle transfer </a>
<a title="EMJ Reproductive Health 4.1 page 93" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=93"> Likewise, other OT cases intended as infertility </a>
<a title="EMJ Reproductive Health 4.1 page 94" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=94"> membrane in oocytes in the prophase of meio</a>
<a title="EMJ Reproductive Health 4.1 page 95" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=95"> disease prevention (use for infertility treatment</a>
<a title="EMJ Reproductive Health 4.1 page 96" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=96"> Table 2 continued. Jurisdiction Year of Oviedo Co</a>
<a title="EMJ Reproductive Health 4.1 page 97" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=97"> with a high mtDNA mutation load. In addition, PGD</a>
<a title="EMJ Reproductive Health 4.1 page 98" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=98"> or even across generations may be necessary to co</a>
<a title="EMJ Reproductive Health 4.1 page 99" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=99"> 2001;76:S67-8. </a>
<a title="EMJ Reproductive Health 4.1 page 100" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=100"> Coming soon. EMJ provides influent</a>
<a title="EMJ Reproductive Health 4.1 page 101" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=101"> Reproductive Function and Fertility in Women </a>
<a title="EMJ Reproductive Health 4.1 page 102" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=102"> defect. Consequently, this form of CAH results in</a>
<a title="EMJ Reproductive Health 4.1 page 103" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=103"> CAH is known to alter the funct</a>
<a title="EMJ Reproductive Health 4.1 page 104" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=104"> Fertility in Women with Classic Congenital Adrena</a>
<a title="EMJ Reproductive Health 4.1 page 105" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=105"> increase the risk of future adrenal crises </a>
<a title="EMJ Reproductive Health 4.1 page 106" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=106"> developing fetal brain and postnatal growth </a>
<a title="EMJ Reproductive Health 4.1 page 107" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=107"> 26. Wilson JD. The role of androgens in </a>
<a title="EMJ Reproductive Health 4.1 page 108" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=108"> Active Selection and Single Embryo Transfer: </a>
<a title="EMJ Reproductive Health 4.1 page 109" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=109"> of transfer procedures and to reduce the risk of </a>
<a title="EMJ Reproductive Health 4.1 page 110" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=110"> It is postulated that embryo selection is more ef</a>
<a title="EMJ Reproductive Health 4.1 page 111" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=111"> Trial </a>
<a title="EMJ Reproductive Health 4.1 page 112" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=112"> presented, comparing PGT-A to a conventional morp</a>
<a title="EMJ Reproductive Health 4.1 page 113" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=113"> The number of women for whom the cycle cost was m</a>
<a title="EMJ Reproductive Health 4.1 page 114" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=114"> (35 of 105) (OR: 1.175 [0.662–2.085]; p=0.5285). </a>
<a title="EMJ Reproductive Health 4.1 page 115" href="https://secure.viewer.zmags.com/publication/bc7eeaf8?page=115"> 23. ESHRE. Focus on Reproduction. 2017. 24. </a>
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