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BioProcess
International
DIGITAL EDITION
ARCHIVE
BioProcess
International
GENE
THERAPY
October 2023
DNA Synthesis: Is the Future Chemical
or Enzymatic? . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1
Mark Behlke
Analytical Method Validation Challenges for
Advanced Therapies: Using Gene Therapies
As an Example . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4
Patrick Nieuwenhuizen and Christopher Rogers
PRODUCTION Working Toward an AAV Platform: Challenges,
Threats, and Opportunities . . . . . . . . . . . . . . . . . . . . . 8
Mégane Denu, Quentin Bazot, and Alengo
AND ANALYSIS Nyamay'antu
Modern Sensor Technologies f
BioProcess International DIGITAL EDITION ARCHIVE
BioProcess International GENE THERAPY October
Quality. Trust ours to enable yours. 17of17
DNA Synthesis Chemical, Enzymatic, or Both? Mar
Scientists use chemical synthesis to manufa
IT ALL STARTS WITH QUALITY Nearl
Analytical Method Validation Challenges for Advan
measuring them consistently help to support regul
Techniques such as analytical ultracentrifugation
Access Complete Article Archives and Multimedia C
Working Toward an AAV Platform Challenges, Threa
Figure 2 (TOP AND BOTTOM): A small-scale design o
Figure 3: Performance using the best transfection
analyzing, fitting, and predicting optimized cond
Overcoming Obstacles in Viral-Vector Manufacturin
Molecular detection by digital polymerase chain r
Modern Sensor Technologies for Viral-Vector Manuf
Figure 3: A traditional dual-wavelength UV sensor
Independent News and Expert Views for the Biophar
Accelerate Your Path to Market with Single-Use Te
A HEALTHY WORLD WITH AJINOMOTO BIO-PHARMA SERVIC