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<br /> BioProcess<br /> International<br /> DIGITAL EDITION<br /> ARCHIVE<br /> New antibody<br /> formats on<br /> the block<br /> Biopharma researchers developing inno-<br /> vative target molecules rely on safe and<br /> HIˉFLHQWSXULˉFDWLRQSURFHVVHVDQGFORVH<br /> collaboration with Tosoh Bioscience.<br /> #ChromatographyExperts<br /> New Antibody Formats on the Block<br /> More Complex Modalities Demand Innovation in Manufacturing and Purification<br /> Romain Dabre<br /> O<br /> ver the past 15 years, monoclonal antibodies (MAbs)<br /> have dominated the biopharmaceutical market, but<br /> now alternative antibody formats are emerging and<br /> moving through company pipelines. These include MAb<br /> fragments, single-chain fragment antibodies, and modified<br /> antibodies — e.g., antibody–drug conjugates (ADCs),<br /> engineered antibodies, and bispecific antibodies.<br /> For conventional MAbs, drug companies <a title="September 2021 - Special Report - Tosoh Bioscience page 1" href="https://secure.viewer.zmags.com/publication/755651a2?page=1"> BioProcess International DIGITAL EDITION ARCHIVE</a> <a title="September 2021 - Special Report - Tosoh Bioscience page 2" href="https://secure.viewer.zmags.com/publication/755651a2?page=2"> New antibody formats on the block Biopharma rese</a> <a title="September 2021 - Special Report - Tosoh Bioscience page 3" href="https://secure.viewer.zmags.com/publication/755651a2?page=3"> New Antibody Formats on the Block More Complex M</a> <a title="September 2021 - Special Report - Tosoh Bioscience page 4" href="https://secure.viewer.zmags.com/publication/755651a2?page=4"> Improved Capture of Antibody Fragments Romain D</a> <a title="September 2021 - Special Report - Tosoh Bioscience page 5" href="https://secure.viewer.zmags.com/publication/755651a2?page=5"> Figure 1: Chromatograms of the protein L capture </a> <a title="September 2021 - Special Report - Tosoh Bioscience page 6" href="https://secure.viewer.zmags.com/publication/755651a2?page=6"> Figure 4: Pressure-flow curve for Toyopearl AF-rP</a> <a title="September 2021 - Special Report - Tosoh Bioscience page 7" href="https://secure.viewer.zmags.com/publication/755651a2?page=7"> Efficient Biopharmaceutical Partnerships A Key t</a> <a title="September 2021 - Special Report - Tosoh Bioscience page 8" href="https://secure.viewer.zmags.com/publication/755651a2?page=8"> Other essential factors include guaranteed delive</a> <a title="September 2021 - Special Report - Tosoh Bioscience page 9" href="https://secure.viewer.zmags.com/publication/755651a2?page=9"> #CHROMATO GRAPHY EXPERTS Efficiently purify an</a>